Smaller increases of FSH induce an increase in the aromatase activity of these granulosa cells, which converts most of the testosterone to estradiol for secretion into the circulation. Therapeutic modalities New chemical entities Biopharmaceuticals Vaccines Advanced therapies Medical device testing Veterinary medicines. Retrieved September 11, Home Pharmaceutical development Crop protection Chemical Research models and services Teklad diet, bedding and enrichment. Puberty is the process of physical changes through which a child 's body matures into an adult body capable of sexual reproduction. The median age of menarche for a population may be an index of the proportion of undernourished girls in the population, and the width of the spread may reflect unevenness of wealth and food distribution in a population.